What Is Cellular Metabolism?
Your body is a complex network of interconnected organs that perform individual functions to support the systems and processes that make up your existence. Respiration, digestion, bone regeneration, metabolism — they’re all examples of your body’s ability to function with machine-like precision. That functionality exists at the most basic level as well — your cellular level. Lungs, brain, stomach, bones, blood — everything — is comprised of cells. Cells are the microscopic components that make up organisms and they, like your body, are a collection of various components that work together to perform the processes that sustain life.
The collection of chemical reactions in your body is usually referred to as your metabolism. This process is the sum of all chemical changes that take place within the cells in your body. During digestion, for example, cellular metabolism is what releases energy from nutrients.[1] Cellular metabolism sustains life and allows cells to grow, develop, repair damage, and respond to environmental changes.[2]
Cellular metabolism can break down organic matter, a process known as catabolism. Cellular metabolism can also produce substances, a process referred to as anabolism. To provide a more graspable example, breaking down food so the nutrients can be utilized is a catabolic reaction. The production of proteins from amino acids is an example of an anabolic reaction.[3] In general, breaking down releases energy and building up consumes energy. Amino acids, carbohydrates, and lipids (often called fats) are vital for life. Metabolic reactions either produce these molecules during the construction of cells and tissue or digest them and use them as a source of energy.
Catabolic Cellular Metabolism
Catabolic metabolism breaks down complex organic molecules into more simple molecules. These exergonic reactions are characterized by the release of energy. Catabolism reduces protein, fat, and carbohydrates into amino acids, fatty acids, and simple sugars, respectively. The energy released from catabolic reactions drives anabolic reactions.[4] It’s a process that has three stages:[5]
- Breakdown of complex molecules into their basic building blocks.
- Breakdown of the basic building blocks into even more simple metabolic intermediates.
- "Combustion" of the acetyl groups of acetyl-coenzymeA by the citric acid cycle and oxidative phosphorylation to produce CO2 and H2O. In other words, energy is released.
Anabolic Cellular Metabolism
Whereas catabolic metabolism breaks down molecules into their constituents, anabolic metabolism combines simple substances into more complex substances.[4] When your cells combine amino acids into proteins to produce cells or tissues, that’s anabolism. Anabolic reactions are endergonic reactions, which means they use more energy than they produce.[6]
Although catabolism and anabolism occur independently of each other, they are inextricably linked. Without cellular metabolism, the body’s cells wouldn’t be able to break down or synthesize the compounds needed for energy, growth, function, and healing.
The Role of Cells
Your body is comprised of an incalculable number of cells, and many different types of cells at that. Brain cells are different from blood cells, which are different from bone cells, which are different from skin cells, and so on. Every cell in your body is uniquely suited for a specific purpose. Others send electrochemical messages to the brain.[7,8] Different cells have different features and may even have structural differences depending on their purpose.[9]
Cell Composition
Although cell structure may vary from one to the next, all cells share several basic traits. Organelles are one feature that all cells possess. Organelles are like miniature organs within the cell that perform different specialized functions. For example, mitochondria are a type of organelle responsible for releasing energy. Other examples include the cell nucleus and endoplasmic reticulum.
Plasma Membrane
Encircles the cytoplasm and organelles of the cell and regulates what substances enter and exit the cell.[10, 12]
Cytoplasm
The jelly-like fluid that surrounds the nucleus and holds the organelles in suspension.
Cytoskeleton
A network of long fibers that comprise the cell’s structural framework. The cytoskeleton also acts like a rail system and helps organelles move to where they are needed.[12]
Endoplasmic Reticulum
The endoplasmic reticulum (ER) is a folded maze of flattened sacs which envelops the nucleus. Although the primary function of the ER is to produce important proteins and fats that are used in a variety of ways, the ER actually has two components — the smooth ER and the rough ER. The rough ER assembles proteins. The smooth ER is responsible for detoxifying the cell of waste products and toxins, producing fats, and other important functions.[13]
Golgi Apparatus
Accepts vesicles, of packages of cell-generated products, from the ER and repacks them to be sent outside the cell. It also is responsible for creating lysosomes.[14]
Lysosomes and Peroxisomes
Lysosomes and peroxisomes are the recycling centers of the cell, refashioning the old, worn-out components.[15]
Mitochondria
Mitochondria are the powerhouses of the cell and when they're functioning normally they convert nutrients into energy. When mitochondria fail, however, energy production is impaired and that can affect any number of important processes within the cell and the body as a whole. Inefficient mitochondria may be due to poor nourishment, genetics, environmental toxins, or disease.[16]
Nucleus
Nestled within the folds of the ER is the nucleus. This organelle is the cell’s command center and contains DNA, including the noncoding telomeres that protect chromosomes. The cell will grow, mature, divide or die based on the instructions it receives from the nucleus.[12]
Ribosomes
Ribosomes interpret DNA information and create proteins.
How to Support Cellular Function
Cellular function directly affects how you feel. If your body is operating poorly at the cellular level, it’s a sure bet your overall well-being will be affected.
Supporting cellular function in your body really is a “garbage in, garbage out” proposition. If your diet isn’t balanced and fails to provide essential nutrients, then your cells aren’t being given the fuel they need. If your nutrient intake is incomplete or inconsistent, organic supplements can help fill the gaps.
Vitamin B12, in particular, is a nutrient that plays a very important role in supporting energy levels and metabolic function. Many people don’t get enough vitamin B12 and, as a result, their energy levels suffer. If you feel chronically fatigued, you may benefit from adding a B12 supplement to your diet.[17]
Vitamin D also supports normal cellular function.[19] It’s difficult to get enough vitamin D in your diet but with adequate skin exposure to sunlight (UVB rays), your body can produce vitamin D.[19] Regular exercise can also boost your health and well-being in many ways; improving cellular function is one of them.[20] It’s important to stay hydrated and consume plenty of clean, purified water. Simply put, hydrated cells function better.
For extra support, we’ve formulated Ultimate Cellular Health. It’s a dietary supplement designed to protect mitochondria, facilitate cellular metabolism, sustain healthy cell cycles, and guard against DNA damage. Cellular Health contains some of the strongest antioxidants available and one of its ingredients, BioPQQ, may protect DNA by supporting telomere structure. Supporting telomere integrity is one of the best ways to defend against the cellular aging that weakens cell metabolism.[21]
References (21)
- Kimball, John W. "Cell Metabolism." Biology (Kimball), LibreTexts, 18 Jan. 2023. Web. 9 Oct. 2024.
- “Cellular Respiration.” Gsu.edu. n.d. Web. 19 Aug. 2016.
- Pearson Education, Inc. Mossmanc Chapter 23. N.p.: Pearson Education, 2010. Web. 19 Aug. 2016.
- “Chemistry for Biologists: Metabolism and energy.” RSC | Advancing the Chemical Sciences. n.d. Web. 19 Aug. 2016.
- “Cellular Respiration.” COD.edu. n.d. PDF. 19 Aug. 2016.
- “Rate of Exergonic Reactions.” City University of New York. n.d. Web. 19 Aug. 2016.
- Jiang, Yong, et al. "The Role of Autophagy in Cancer: Therapeutic Implications." Frontiers in Oncology, U.S. National Library of Medicine, 17 Mar. 2021. Web. 9 Oct. 2024.
- National Cancer Institute. "Cellular Metabolism." NCI Dictionary of Cancer Terms, U.S. Department of Health and Human Services, n.d. Web. 9 Oct. 2024.
- HULL, DAVID. “THE STRUCTURE AND FUNCTION OF BROWN ADIPOSE TISSUE.” British Medical Bulletin 22.1 (1966): 92–96. Web. 19 Aug. 2016.
- Spector, Arthur A, and Mark A Yorek. Membrane Lipid Composition. 2002. Web. 19 Aug. 2016.
- “SEER Training: Cell Function.” National Institute of Health, National Cancer Institute, SEER Training Modules. n.d. Web. 19 Aug. 2016.
- “What is a cell?” NIH Genetics Home Reference. Genetics Home Reference, 16 Aug. 2016. Web. 19 Aug. 2016.
- “Molecular Expressions Cell Biology: Endoplasmic Reticulum.” Florida State University. 1995. Web. 19 Aug. 2016.
- “Golgi Apparatus.” Georgia State University. n.d. Web. 19 Aug. 2016.
- Cooper, Geoffrey M. Lysosomes. N.p.: Sinauer Associates, 2000. Web. 19 Aug. 2016.
- “Mitochondrial DNA Analysis.” 2007. Web. 19 Aug. 2016.
- “Office of Dietary Supplements - Dietary Supplement Fact Sheet: Vitamin B12.” NIH. 11 Feb. 2016. Web. 19 Aug. 2016.
- Harinarayan CV, Arvind S, Joshi S, Thennarasu K, Vedavyas V, Baindur A. IMPROVEMENT IN PANCREATIC β-CELL FUNCTION WITH VITAMIN D AND CALCIUM SUPPLEMENTATION IN VITAMIN D-DEFICIENT NONDIABETIC SUBJECTS. Endocr Pract. 2014 Feb;20(2):129-38.
- Holick MF. Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease. Am J Clin Nutr. 2004 Dec;80(6 Suppl):1678S-88S.
- "Exercise and immunity." Medline Plus. Review Date 1/10/2016.
- Fossel, Michael, Greta Blackburn, and Dave Woynarowski. AARP the Immortality Edge: Realize the Secrets of Your Telomeres for a Longer Healthy Life. N.p.: John Wiley, 2012. eBook. 19 Aug. 2016.
†Results may vary. Information and statements made are for education purposes and are not intended to replace the advice of your doctor. If you have a severe medical condition or health concern, see your physician.
Dr. Edward Group, DC
FOUNDER | HEALER | ADVOCATEDr. Group, DC is a healer and alternative health advocate, and an industry leader and innovator in the field of natural health who is dedicated to helping others. He is a registered doctor of chiropractic (DC), a naturopathic practitioner (NP), and proud alum of Harvard Business School and MIT Sloan School of Management. Dr. Group, DC is the founder of Global Healing – a mission and vision he has shared through best-selling books and frequent media appearances. He aims to spread his message of positivity, hope, and wellness throughout the world.